The best semaglutide providers in 2026

We compared every semaglutide programme we could get a straight price out of, then ranked them on what you are billed in month two rather than what the advert promises in month one.

That distinction decides this list. Half the programmes here advertise a medication price and charge a membership on top of it, so a $99 headline becomes a $198 statement. Coreage Rx finishes first because it does not do that — and because, once the fees are added, nothing else is close on cost.

The ranking

Scores come from the weighted rubric on how we rate. Prices checked 2026-09-18.

1. Coreage Rx — Best overall on true monthly cost

$149 a month, all in. Eden advertises the same $99. Mochi advertises $99. Both then charge a membership that renews at $79 to $99 a month, which roughly doubles the real figure. Coreage Rx charges no membership, so $99 stays $99 on the annual plan and $149 month-to-month. That single structural difference is why it tops our semaglutide table.

The $99 and $149 rates are annual-plan prices. If you want month-to-month, budget $149 and $199 instead, and check the refund terms before prepaying a year. Full detail in our Coreage Rx semaglutide review.

2. Mochi Health — Insurance concierge support

$178 a month, all in. That puts the working figure near $178 a month, dropping toward $165 if you prepay a longer term. It is not the cheapest — Coreage Rx at $99 on the annual plan with no membership is — but it is the cheapest programme here that also comes with an insurance team.

Labs are billed separately. Ask what the clinic expects to order before you sign up. Full detail in our Mochi Health semaglutide review.

3. Hims & Hers — Widest range of formats

$188 a month, all in. The cheap figures — $49, $79 — describe oral kits. The weekly injection is the product most people actually mean, and it sits nearer $199 before the $39 membership, so roughly $188 to $238 a month depending on which tier you land in. The membership applies either way.

The advertised entry prices and the membership are separate charges. Add $39/month to whatever medication figure you were quoted. Full detail in our Hims & Hers semaglutide review.

4. Ro — Branded medication with insurance help

$448 a month, all in. The membership is $39 for the first month, then $149, and it buys care rather than medication. Branded Wegovy through NovoCare has been offered at $199 a month for the first two fills through the end of 2026 and $349 a month afterwards, so an insured patient might pay little while a cash payer pays close to $500 all in.

The membership and the medication are two separate bills. A $39 first month does not mean a $39 prescription. Full detail in our Ro semaglutide review.

5. Zealthy — Low-cost entry with insurance routing

$151 a month, all in. That is more than Coreage Rx at $99 on the annual plan, and considerably less than Eden or Mochi once their memberships renew. The $39 first month lowers the barrier to trying it without the usual trap of a teaser rate that triples.

The widely quoted $25/month is an insured price. Cash payers should plan on $151+ for semaglutide. Full detail in our Zealthy semaglutide review.

6. LifeMD — Insurance coordination

$149 a month, all in. It is $75 for the first month and $149 a month afterwards, with the annual plan holding nearer $75. Medication is separate unless covered. Where coverage lands, patient cost for branded semaglutide can drop to roughly $25 a month, which is the scenario the marketing is built around.

If your insurer declines, the $149/month programme fee still applies and the medication is extra. Full detail in our LifeMD semaglutide review.

7. Noom Med — Behaviour change alongside medication

$149 a month, all in. Microdosing means deliberately low doses — below the levels used in the trials that produced the weight-loss figures people have read about. Medication is included at that price, which is genuinely unusual. But comparing $79 microdose against $99 full-dose compounded semaglutide is comparing two different treatments.

A $79 microdose programme is not the same treatment as 10 mg tirzepatide. Check the dose before comparing on price. Full detail in our Noom Med semaglutide review.

8. Eden — Low advertised medication price

$198 a month, all in. The $39 introductory membership becomes $99 a month. That means the real recurring figure is around $198, not $99. Coreage Rx advertises the same $99 with no membership at all, which is why the two sit at opposite ends of our table despite identical headline numbers.

The $99 semaglutide headline becomes roughly $198/month once the membership renews at its ongoing rate. Full detail in our Eden semaglutide review.

What semaglutide actually does

A weekly injection that activates the GLP-1 receptor, slowing stomach emptying and reducing appetite signalling.

In STEP-1, adults on 2.4 mg lost an average of about 14.9% of body weight over 68 weeks.

In the SURMOUNT-5 head-to-head trial semaglutide produced less weight loss than tirzepatide, averaging 33.1 lb (15.0 kg) against 50.3 lb (22.8 kg).

Side effects reported most often: Nausea, vomiting, diarrhoea and constipation, usually worst in the first weeks and after dose increases. More on that in our plain-English guide to semaglutide.

A word about compounded medication

Compounded GLP-1s are no longer the freely marketed product they were in 2024. They remain legal in a narrower form, and the rules changed again in 2026.

• A 503A pharmacy may still compound a GLP-1 for an individual patient when there is a documented, patient-specific clinical reason — for example a required dose or formulation that the approved product does not provide.
• Routinely marketed, off-the-shelf compounded GLP-1 sold like a consumer product is not permitted under that framework.
• If the 503B Bulks List proposal is finalised, outsourcing facilities would lose the pathway they have been using to produce these drugs in volume.
• Compounded versions are not FDA-approved. The agency does not review them for safety, effectiveness or manufacturing quality the way it reviews Zepbound or Wegovy.

We set the full timeline out in is compounded still legal, which we update whenever the FDA moves.

How we picked

• True monthly cost (30%) — What you actually pay in month two — medication plus membership plus anything billed separately. Advertised teaser rates score nothing here.
• Price honesty (20%) — Whether the renewal price is visible before you hand over a card, and whether the number at checkout matches the number in the ad.
• Clinical support (20%) — Who prescribes, how you reach them between visits, and whether dose changes are reviewed by a person or applied on a schedule.
• Pharmacy sourcing (15%) — Whether the provider names its pharmacy, states the 503A/503B pathway, and offers FDA-approved options alongside compounded ones.
• Cancelling (15%) — How hard it is to stop. Prepaid multi-month plans that cannot be refunded are marked down here.

We do not accept payment for placement in this table. We do earn a commission if you sign up with Coreage Rx through our link, which is disclosed at the top of this page and in full on our advertising disclosure.